The main way into and out of Boston is Logan Airport, which is serviced by numerous airlines (see list). The airport is right across Boston Harbor from downtown Boston, so unless you hit really bad traffic, you can be at your hotel within 15 minutes by cab. There is also an airport subway stop - after you get your bags, go outside for the free Massport shuttle to the subway.
Southwest Airlines offers lower-cost fares to and from T.F. Green Airport outside of Providence, RI, about a 40-minute drive from Boston, and Manchester Airport in New Hampshire, about an hour north of Boston.
Bonanza and Greyhound provide service to and from Boston, arriving and departing at South Station (there's also a stop off Rte. 128 at the end of the Riverside branch of the Green Line trolley in Newton). Several bus and van companies now offer low-cost bus service between the Chinatowns in New York and Boston; click here for more info.
The main routes into Boston are I-90 (also known as the Massachusetts Turnpike) from the west and I-95 and I-93 from the north and south.
If you're coming from New York or points south, however, don't take I-95 all the way, unless there are places in Connecticut or Rhode Island you want to see. I-84 to I-90 is a much faster route.
If you can, try to avoid rush hour (roughly 7 to 9 a.m. and 4 to 7 p.m. on workdays). Also, be aware that on several major roadways, including parts of I-93 south of the city and Rte. 128 (also known as I-95), the shoulder (known locally as "the breakdown lane") turns into a travel lane during rush hour. Rte. 128 has several emergency pulloffs should you be unlucky enough to break down in the breakdown lane during rush hour.
Note: While online mapping services can get you to the Boston area, do NOT rely on them for plotting routes once you're in the city. There's something about Boston's road system that drives them into apoplexy and there's a good chance you could get bum directions from them. Ask your hotel concierge or host for directions.
Amtrak has frequent train service to Boston from New York and other points in the Northeast Corridor. The trip from New York takes about 3 1/2 hours on Acela Express trains, about 4 hours on other trains. There's also twice-daily service between Boston and Chicago.
Note: Amtrak has three Boston stops. Rte. 128 is about 12 miles from downtown and is a good place to get off if you have family or friends in the western or southern suburbs to meet you. Back Bay Station is in the Back Bay, convenient to the Back Bay and the South End (and the Orange Line subway). The final stop is South Station, near the financial district (and the Red Line subway).
Getting here is easy - Boston is linked to the rest of the world by numerous airlines, bus companies, Amtrak and interstate highways.